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KMID : 0367419940370091196
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Journal of Korean Pediatric Society
1994 Volume.37 No. 9 p.1196 ~ p.1204
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Longitudinal Change of Cerebral Blood Flow Velocity in Neonates with Perinaltal Asphyxia and Hypoxic-Ischemic Encephalopathy with Doppler Technique
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박국인
한동관/이준수/남궁란/이철
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Abstract
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Fifty-three full-term, preterm, term-SGA newborn infants with perinatal asphyxia and 16 full-term infants with hypoxic-ischemic encephalopathy were studied with color Doppler sonography to assess the postnatal change of the cerebral blood flow
velocity
(CBFV) longitudinally. A control group of 81 healthy infants also had CBFV recordings during the lst week of life Pourcelot Resistance index (PI) and area under the velocity curve (AUVC) were calculated to quantitate changes in CBFV.
PI values of full-term infants with perinatal asphyxia were within normal range, but AUVC values were higher on day 1 and 7 than those of normal full-term infants. In preterm and full-term SGA infants with perinatal asphyxia, PI and AUVC values
were
also within normal range during the lst week of life. Full-term and preterm infants with perinatal asphyxia showed no significant difference in PI and AUVC values according to the degree of asphyxia.
The full-term infats with hypoxic-ischemic encephalopathy showed significant decreased PI and increased AUVC values from the 2nd day of life of life compard with those of normal and asphyxiated infants reflecting high cerebral blood flow state.
We
also
found a relationship between disturbances of consciousness and the PI. The prediction of occurrence of hypoxic-ischemic encephalopathy by abnormal Doppler studies(PI≤0.55) showed a sensitivity of 100% and a specificity of 88%.
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KEYWORD
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